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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY6
All Species:
9.09
Human Site:
S45
Identified Species:
20
UniProt:
O43306
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43306
NP_056085.1
1168
130615
S45
F
C
T
P
R
Y
M
S
C
L
R
D
A
E
P
Chimpanzee
Pan troglodytes
XP_509033
1166
130086
S45
F
C
T
P
R
Y
M
S
C
L
R
D
A
E
P
Rhesus Macaque
Macaca mulatta
XP_001102486
1168
130543
S45
F
C
T
P
R
Y
M
S
C
L
R
D
A
E
P
Dog
Lupus familis
XP_534819
1166
130415
C45
C
T
P
R
Y
M
S
C
L
R
D
A
Q
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q01341
1165
130300
C45
C
A
P
R
Y
M
S
C
L
K
N
A
E
P
P
Rat
Rattus norvegicus
Q03343
1166
130488
C45
C
A
P
R
Y
M
S
C
L
K
N
V
E
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511957
593
65761
Chicken
Gallus gallus
Q9DGG6
1334
149273
K46
A
L
S
A
K
R
C
K
Y
S
I
S
S
S
C
Frog
Xenopus laevis
P98999
1305
145393
I46
S
R
R
C
K
Y
S
I
S
S
S
C
S
S
G
Zebra Danio
Brachydanio rerio
XP_002666536
1123
127693
R45
P
R
Y
M
S
C
L
R
D
P
E
S
M
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122246
1014
113539
N28
L
K
L
F
L
D
G
N
Q
R
F
F
D
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.9
96.4
N.A.
94.1
93.3
N.A.
42.6
25.6
25.5
69.7
N.A.
N.A.
43.4
N.A.
N.A.
Protein Similarity:
100
97.2
99.5
97.5
N.A.
96
95.8
N.A.
45.6
41.5
42
79.4
N.A.
N.A.
59.7
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
0
0
6.6
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
0
20
20
13.3
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
10
0
0
0
0
0
0
0
19
28
0
10
% A
% Cys:
28
28
0
10
0
10
10
28
28
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
10
28
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
19
37
0
% E
% Phe:
28
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
19
0
0
10
0
19
0
0
0
0
0
% K
% Leu:
10
10
10
0
10
0
10
0
28
28
0
0
0
0
10
% L
% Met:
0
0
0
10
0
28
28
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
19
0
0
0
0
% N
% Pro:
10
0
28
28
0
0
0
0
0
10
0
0
0
28
55
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
19
10
28
28
10
0
10
0
19
28
0
0
0
0
% R
% Ser:
10
0
10
0
10
0
37
28
10
19
10
19
19
19
0
% S
% Thr:
0
10
28
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
28
37
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _